The Structure of L-Mimosine, an L-DOPA Analogue.
نویسندگان
چکیده
منابع مشابه
L-dopa
Oleh Hornykiewicz was born in 1926 in Sykhiw, Poland (now Ukraine). In 1951, he received his M.D. degree from the University of Vienna and joined the faculty of his alma mater the same year and has worked there ever since. He also served for twenty years as chairman of the Institute of Biochemical Pharmacology. In 1967, he began a long association with the University of Toronto in Canada and, i...
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to include the "why" of procedures, but rather presents step-by-step instructions and recipes for the bench technologist. The first of the three sections deals with biochemical identification tests, from acetate utilization to Voges-Proskauer. Each includes descriptions of purpose, principle, mechanisms, equipment and reagents, method, and interpretation. The format is short, lucid, and informa...
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L-Dopa is the drug of choice in the treatment of Parkinson's disease but it has dose related adverse effects such as nausea, vomiting, orthostatic hypotension, end of dose deterioration, on off phenomena and on chronic therapy motor complications synonymous to parkinsonism. Mucuna pruriens (M.P) commonly known as velvet beans or cowitch are used in case of spasms associated with Parkins onism. ...
متن کاملHypotension caused by L-dopa.
In 20 patients with idiopathic Parkinsonism maximum tolerated doses of L-dopa were found to induce a mean reduction in blood pressure (erect systolic) of 19.3 mm.Hg, without any significant change in pulse rate. This hypotension may be due to dopamine, acting on adrenergic nerve endings or on the central nervous system itself.
متن کاملThe L-dopa response in vascular parkinsonism.
OBJECTIVE To determine whether a positive L-dopa response in vascular parkinsonism (VP) is correlated with the presence of nigrostriatal pathology due to either vascular damage or neuronal cell loss. METHODS Seventeen patients with pathologically confirmed VP were selected from the pathological collection of the Queen Square Brain Bank for Neurological Disorders, and their L-dopa response dur...
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ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1973
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.27-0164